OR-019 VEGF-B inhibits skeletal muscle apoptosis after exercise in Chronic heart failure rats
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چکیده
منابع مشابه
Attenuated Fatigue in Slow Twitch Skeletal Muscle during Isotonic Exercise in Rats with Chronic Heart Failure
During isometric contractions, slow twitch soleus muscles (SOL) from rats with chronic heart failure (chf) are more fatigable than those of sham animals. However, a muscle normally shortens during activity and fatigue development is highly task dependent. Therefore, we examined the development of skeletal muscle fatigue during shortening (isotonic) contractions in chf and sham-operated rats. Si...
متن کاملExercise training prevents skeletal muscle afferent sensitization in rats with chronic heart failure.
An exaggerated exercise pressor reflex (EPR) contributes to exercise intolerance and excessive sympathoexcitation in the chronic heart failure (CHF) state, which is prevented by exercise training (ExT) at an early stage in the development of CHF. We hypothesized that ExT has a beneficial effect on the exaggerated EPR by improving the dysfunction of muscle afferents in CHF. We recorded the disch...
متن کاملExercise training has restorative potential on myocardial energy metabolism in rats with chronic heart failure
Objective(s): Exercise training is a well-known accelerator for the treatment of chronic heart failure (CHF). The current study aimed to investigate the restorative effects of aerobic interval training (AIT) intervention on myocardial energy metabolism in CHF rats. Materials and Methods: Post-myocardial infarction (MI) heart failure animal model was established. The Sprague-Dawley rats were ran...
متن کاملSkeletal muscle metaboreceptor exercise responses are attenuated in heart failure.
BACKGROUND Resting sympathetic nervous system activity is increased in heart failure. Whether sympathetic nervous system responses during exercise are increased is controversial. Furthermore, the role of muscle metaboreceptors and central command in regulating sympathetic outflow has been largely unexplored. METHODS AND RESULTS Muscle sympathetic nerve activity (MSNA, peroneal nerve) was meas...
متن کاملSkeletal muscle response to exercise training in congestive heart failure.
To examine the ability of the skeletal muscle of congestive heart failure (CHF) patients to adapt to chronic exercise, five patients performed localized nondominant wrist flexor training for 28 d. Inorganic phosphate (Pi) and phosphocreatine (PCr) were monitored by magnetic resonance spectroscopy in both forearms at rest and during submaximal wrist flexion exercise at 6, 12, 24, and 36 J.min-1 ...
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ژورنال
عنوان ژورنال: Exercise Biochemistry Review
سال: 2018
ISSN: 2593-7588
DOI: 10.14428/ebr.v1i2.9203